IHydroxypropyl methylcellulose (HPMC) yi-ether yeselulosi esetyenziswa ngokubanzi eyaziwa ngeempawu zayo ezigqwesileyo zokujiya.Isetyenziswa ngokubanzi kumashishini ahlukeneyo, kuquka ukwakhiwa, amayeza, ukutya kunye nokunyamekela komntu.Kweli phepha, sigxile kwisiphumo esityebileyo se-HPMC kwaye siphonononge izinto eziphembelela ukuziphatha kwayo ukutyeba.
Indlela yokujiya ye-HPMC yile:
Isiphumo esityebileyo se-HPMC sibalelwa kulwakhiwo olukhethekileyo lwemolekyuli.I-molecule ye-HPMC iqulethe umqolo wamatyathanga e-cellulose kunye ne-hydroxypropyl kunye namaqela e-methyl aqhotyoshelweyo.Xa i-HPMC ihlakazwe emanzini okanye kwezinye izinyibilikisi, amatyathanga e-cellulose afunxa amanzi kwaye adumbe, okukhokelela ekubunjweni kwesakhiwo senethiwekhi ye-3D.Le nethiwekhi ibamba i-solvent kwaye yandisa i-viscosity okanye ukusasazwa kwesisombululo.
Izinto ezichaphazela isiphumo sokujiya:
Ugxininiso: Uxinzelelo lwe-HPMC kuqulunqo ludlala indima ebalulekileyo kwisiphumo sayo sokuqina.Njengoko uxinaniso lukhula, iimolekyuli ezininzi ze-HPMC ziyasebenzisana, ezikhokelela ekuphuculweni kwe-viscosity kunye nokuqina.
Ubunzima bemolekyuli: Ubunzima bemolekyuli ye-HPMC buchaphazela iimpawu zayo ezityebileyo.Ubunzima bemolekyuli obuphezulu I-HPMC ngokuqhelekileyo ibonisa impembelelo eyomeleleyo xa ithelekiswa namabanga asezantsi obunzima bemolekyuli.
Ubushushu: Ubushushu bunokuchaphazela ukuziphatha okutyebileyo kwe-HPMC .. Ngokubanzi, ukwandisa ubushushu kunciphisa i-viscosity kunye nemiphumo yokuqina kwesisombululo se-HPMC. Nangona kunjalo, esi siphumo sinokuhluka ngokuxhomekeke kwibakala elithile le-HPMC.
I-pH: I-pH yesisombululo inokuchaphazela isiphumo sokuqina kwe-HPMC. Amanye amabakala e-HPMC angabonisa ukujiya okuphuculweyo kwiindidi ze-pH ezithile, ngelixa ezinye zinokuba nobuntununtunu ngakumbi kutshintsho lwe-pH.
I-Shear Rate: Umlinganiselo we-shear, okanye umlinganiselo apho isisombululo siphantsi koxinzelelo lwemishini, sinokuchaphazela ukuziphatha kokuqina kwe-HPMC. amazinga okucheba, ezifana ngexesha ukuvuselela okanye isicelo, viscosity kunokuncipha ngenxa yokucheba ukwaphula isakhiwo eyenziwe HPMC.
Usetyenziso lwe-HPMC eThickened:
Isiphumo esityebileyo se-HPMC siyenza isongezo esixabisekileyo kwizicelo ezininzi.Ezinye izicelo eziqhelekileyo ziquka:
Ulwakhiwo: I-HPMC isetyenziselwa izinto ezinesamente ezifana nodaka kunye nokunamathiswa kweethayile ukuphucula ukusebenza kwazo, ukugcinwa kwamanzi kunye nokuxhathisa i-sag.
Pharmaceuticals: I-HPMC iqashwe njengento etyebisayo ekunqunyanyisweni komlomo, izisombululo zamehlo kunye neejeli zamehlo, ukubonelela ngokungaguquguquki okufunwayo kunye nokuhanjiswa kwechiza okuphuculweyo.
Ukutya & neziselo: I-HPMC isetyenziswa kwiimveliso zokutya ezahlukeneyo ezifana neesosi, izinxibo kunye nezimuncumuncu ukuqinisa ukuthungwa, ukuzinza kunye nokuziva komlomo.
Ukhathalelo loMntu kunye neZithambiso: I-HPMC ifumana izicelo kwiimveliso zokhathalelo lomntu, kubandakanywa iikhrimu, ii-lotions kunye nokulungiswa kweenwele, njenge-thickener, i-stabilizer kunye ne-agent-forming agent.
IHydroxypropyl methylcellulose (HPMC) ibonisa iipropati ezibalulekileyo zokujiya ngenxa yesakhiwo sayo esisodwa semolekyuli kunye nokusebenzisana namanzi.Ukuqonda izinto eziphembelela ukutyeba kwesiphumo se-HPMC, njengokuxinana, ubunzima bemolekyuli, ubushushu, i-pH, kunye nesantya sokucheba, kubalulekile ekuqulunqweni kweemveliso ezine-viscosity efunwayo kunye nokungaguquguquki. uluhlu olubanzi lwamashishini, ukubonelela ukusebenza okuphuculweyo kunye neempawu eziphuculweyo zemveliso.
